Peer Reviewed Studies
We are currently collating sources of the latest research and peer reviewed publications about HSCT. We will add new articles as soon as we find them.
May
2023
Long-term results of autografting persons with multiple sclerosis are better in those not exposed to prior disease-modifying therapies
Daniela Sánchez-Bonilla,
Max Robles-Nasta,
Moisés Manuel Gallardo-Pérez,
Edgar J. Hernández-Flores,
Merittzel Montes-Robles,
María de Lourdes , Pastelín-Martínez
Solón, Javier Garcés-Eisele,
Juan Carlos Olivares-Gazca,
Guillermo J. Ruiz-Delgado,
Guillermo J. Ruiz-Argüelles
Multiple Sclerosis & Related Disorders
December
2022
Hematopoietic Stem Cell Transplantation in People With Active Secondary Progressive Multiple Sclerosis
Giacomo Boffa, Alessio Signori, Luca Massacesi , Alice Mariottini , Elvira Sbragia, Salvatore Cottone, Maria Pia Amato, Claudio Gasperini, Lucia Moiola, Stefano Meletti, Anna Maria Repice, Vincenzo Brescia Morra , Giuseppe Salemi , Francesco Patti , Massimo Filippi, Giovanna De Luca, Giacomo Lus, Mauro Zaffaroni, Patrizia Sola, Antonella Conte, Riccardo Nistri, Umberto Aguglia, Franco Granella, Simonetta Galgani, Luisa Maria Caniatti, Alessandra Lugaresi, Silvia Romano, Pietro Iaffaldano, Eleonora Cocco, Riccardo Saccardi, Emanuele Angelucci, Maria Trojano, Giovanni Luigi Mancardi, Maria Pia Sormani, Matilde Inglese; Italian BMT-MS Study Group, Italian MS Register
PubMed
July
2022
High-dose immunosuppressive therapy with autologous hematopoietic stem cells transplantation for multiple sclerosis: Current view
Alexey Yu. Polushin, Evgeniya I. Lopatina, Yury R. Zalyalov, Alexander A. Tsynchenko, Natalia A. Totolyan, Alexander D. Kulagin
Pavlov University, St. Petersburg, Russia
Cellular Therapy and Transplantation (CTT)
July
2022
Stem Cell Therapy in Neuroimmunological Diseases and Its
Potential Neuroimmunological Complications
Franz Felix Konen, Philipp Schwenkenbecher
, Konstantin Fritz Jendretzky
, Stefan Gingele
,Lea Grote-Levi, Nora Möhn
, Kurt-Wolfram Sühs 1
, Britta Eiz-Vesper 2
, Britta Maecker-Kolhoff, Corinna Trebst, Thomas Skripuletz,Martin W. Hümmert
Cells
February
2022
Autologous hematopoietic stem cell transplantation vs low-dose immunosuppression in secondary-progressive multiple sclerosis
Alice Mariottini, Giovanni Bulgarini, Benedetta Forci, Chiara Innocenti, Fabrizia Mealli, Alessandra Mattei, Chiara Ceccarelli, Anna Maria Repice, Alessandro Barilaro, Claudia Mechi, Riccardo Saccardi, Luca Massacesi
PubMed
September
2021
Splitting the Total Dose of Cyclophosphamide in Two Blocks Apart during the Conditioning of Autologous Hematopoietic Stem Cell Transplantation in Multiple Sclerosis Results in Diminished Cardiotoxicity: Experience in 1,000 Patients
Juan Carlos Olivares-Gazca, Francisco Guerrero-Pesqueira, Iván Murrieta-Alvarez, Yahveth Cantero-Fortiz, Andrés A León-Peña, José M Priesca-Marín, David Gomez-Almaguer, Andrés Gomez-De-Leon, Guillermo J Ruiz-Delgado, Guillermo J Ruiz-Argüelles
PubMed
September
2021
Autologous ATG-free hematopoietic stem cell transplantation for refractory autoimmune rheumatic diseases: a Latin American cohort
José Carlos Jaime-Pérez , Mariana González-Treviño , Jesús D Meléndez-Flores , Eugenia M Ramos-Dávila , Olga G Cantú-Rodriguez , César H Gutiérrez-Aguirre, Dionicio A Galarza-Delgado, David Gómez-Almaguer
PubMed
July
2021
Autologous hematopoietic stem cell
transplantation with low-intensity
conditioning regimens in relapsing remitting
multiple sclerosis: clinical outcomes and
quality of life
Vladimir Y. Melnichenko, Denis A. Fedorenko,
Tatiana. P Nikitina,
Natalia. M. Porfirieva
Ilya S. Nikolaev,
Tatiana I. Ionova
Cellular Therapy and Transplantation (CTT)
July
2021
New autoimmune diseases after autologous hematopoietic stem cell transplantation for multiple sclerosis
Richard K Burt, Paolo A Muraro, Dominique Farge, Maria Carolina Oliveira, John A Snowden, Riccardo Saccardi, Xiaoqiang Han, Kathleen Quigley, Valquiria Bueno, Daniela Frasca, Denis Fedorenko, Joachim Burman
PubMed
February
2021
Autologous haematopoietic stem cell transplantation and other cellular therapy in multiple sclerosis and immune-mediated neurological diseases: updated guidelines and recommendations from the EBMT Autoimmune Diseases Working Party (ADWP) and the Joint Accreditation Committee of EBMT and ISCT (JACIE)
European Society for Blood and Marrow Transplantation (EBMT) Autoimmune Diseases Working Party (ADWP) and the Joint Accreditation Committee of the International Society for Cellular Therapy (ISCT) and EBMT (JACIE)
PubMed
February
2021
Evaluating the clinical effectiveness of autologous haematopoietic stem cell transplantation versus disease-modifying therapy in multiple sclerosis using a matching-adjusted indirect comparison: an exploratory study from the Autoimmune Diseases Working Party (ADWP) of the European Society of Bone and Marrow Transplantation (EBMT)
P Tappenden, Y Wang, B Sharrack, J Burman, M Kazmi, R Saccardi, I Bermejo, R Harvey, M Badoglio, D Farge, J A Snowden
PubMed
February
2021
Hematopoietic cell transplantation and cellular therapy survey of the EBMT: monitoring of activities and trends over 30 years
Jakob R. Passweg, Helen Baldomero, Christian Chabannon, Grzegorz W. Basak, Rafael de la Cámara, Selim Corbacioglu, Harry Dolstra, Rafael Duarte, Bertram Glass, Raffaella Greco, Arjan C. Lankester, Mohamad Mohty, Régis Peffault de Latour, John A. Snowden, Ibrahim Yakoub-Agha & Nicolaus Kröger for the European Society for Blood and Marrow Transplantation (EBMT)
Nature
February
2021
General information for patients and carers considering haematopoietic stem cell transplantation (HSCT) for severe autoimmune diseases (ADs): A position statement from the EBMT Autoimmune Diseases Working Party (ADWP), the EBMT Nurses Group, the EBMT Patient, Family and Donor Committee and the Joint Accreditation Committee of ISCT and EBMT (JACIE)
European Society for Blood and Marrow Transplantation (EBMT) Autoimmune Diseases Working Party (ADWP) and the Joint Accreditation Committee of the International Society for Cellular Therapy (ISCT) and EBMT (JACIE)
PubMed
August
2020
Stem Cell Therapy for Patients With Multiple Sclerosis Failing Alternate Approved Therapy- A Randomized Study
Sponsor:
Northwestern University
Collaborators:
Uppsala University
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sao Paulo
Information provided by (Responsible Party):
Richard Burt, MD, Northwestern University
ClinicalTrials.gov
September
2019
Autologous haematopoietic stem cell transplantation and other cellular therapy in multiple sclerosis and immune-mediated neurological diseases: updated guidelines and recommendations from the EBMT Autoimmune Diseases Working Party (ADWP) and the Joint Accreditation Committee of EBMT and ISCT (JACIE)
Basil Sharrack, Riccardo Saccardi, Tobias Alexander, Manuela Badoglio, Joachim Burman, Dominique Farge, Raffaella Greco, Helen Jessop, Majid Kazmi, Kirill Kirgizov, Myriam Labopin, Gianluigi Mancardi, Roland Martin, John Moore, Paolo A. Muraro, Montserrat Rovira, Maria Pia Sormani & John A. Snowden for the European Society for Blood and Marrow Transplantation (EBMT) Autoimmune Diseases Working Party (ADWP) and the Joint Accreditation Committee of the International Society for Cellular Therapy (ISCT) and EBMT (JACIE)
Nature
January
2019
Effect of Nonmyeloablative Hematopoietic Stem Cell Transplantation vs Continued Disease-Modifying Therapy on Disease Progression in Patients With Relapsing-Remitting Multiple Sclerosis: A Randomized Clinical Trial
Richard K Burt, Roumen Balabanov, Joachim Burman, Basil Sharrack, John A Snowden, Maria Carolina Oliveira, Jan Fagius, John Rose, Flavia Nelson, Amilton Antunes Barreira, Kristina Carlson, Xiaoqiang Han, Daniela Moraes, Amy Morgan, Kathleen Quigley, Kimberly Yaung, Regan Buckley, Carri Alldredge, Allison Clendenan, Michelle A Calvario, Jacquelyn Henry, Borko Jovanovic, Irene B Helenowski
PubMed
July
2017
Autologous hematopoietic stem cell transplantation in relapsing-remitting multiple sclerosis: comparison with secondary progressive multiple sclerosis
Bonaventura Casanova, Isidro Jarque, Francisco Gascón, Juan Carlos Hernández-Boluda, Francisco Pérez-Miralles, Javier de la Rubia, Carmen Alcalá, Jaime Sanz, Javier Mallada, Angeles Cervelló, Arantxa Navarré, María Carcelén-Gadea, Isabel Boscá, Sara Gil-Perotin, Carlos Solano, Miguel Angel Sanz, Francisco Coret
PubMed
February
2017
NEDA status in highly active MS can be more easily obtained with autologous hematopoietic stem cell transplantation than other drugs
Richard K Burt, Paolo A Muraro, Dominique Farge, Maria Carolina Oliveira, John A Snowden, Riccardo Saccardi, Xiaoqiang Han, Kathleen Quigley, Valquiria Bueno, Daniela Frasca, Denis Fedorenko, Joachim Burman
PubMed
July
2015
Long-term outcomes of autologous hematopoietic stem cell transplantation with reduced-intensity conditioning in multiple sclerosis: physician's and patient's perspectives
Jury L Shevchenko, Alexey N Kuznetsov, Tatyana I Ionova, Vladimir Y Melnichenko, Denis A Fedorenko, Kira A Kurbatova, Gary I Gorodokin, Andrei A Novik
PubMed
February
2010
Autologous hematopoietic stem cell transplantation for autoimmune diseases: an observational study on 12 years' experience from the European Group for Blood and Marrow Transplantation Working Party on Autoimmune Diseases
Dominique Farge, Myriam Labopin, Alan Tyndall, Athanasios Fassas, Gian Luigi Mancardi, Jaap Van Laar, Jian Ouyang, Tomas Kozak, John Moore, Ina Kötter, Virginie Chesnel, Alberto Marmont, Alois Gratwohl, Riccardo Saccardi